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Pregnant and breastfeeding women should also avoid supplementation and focus on dietary sources instead

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Great options include dark leafy greens, whole grains, nuts and seeds

RL: Writing original draft

These channels promote intercellular communication by permitting the release of gliotransmitters such as adenosine triphosphate (ATP) and glutamate, as well as calcium ions (Ca 2+ ), which are essential in neuroinflammatory mechanisms [11]

(ISBN: 978-0-07-149618-6) Keywords Cocaine Toxicology Source: Drug of abuse Mechanism of Action: CNS stimulant blocks the reuptake of catecholamines: dopamine, norepinephrine & serotonin (DAT, NET & SERT transporters) Na and K channel blocker (at slightly higher doses than those blocking reuptake of catecholamines commonly coadministered with ethanol to create cocaethylene which has a longer half-life (and prolonged high) Symptoms: CNS : Euphoria , which may be followed by anxiety & agitation Psychatric symptoms (including paranoia, psychosis & the sensation of something crawling on the skin or itchy skin) Hyperactivity & Seizures (usually self limiting