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Description

The potentially beneficial features of IgE include its affinity for the FcR, expressed by the immune effectors responsible for ADCC and ADCP, and the low levels of normal IgE in the blood, which avoids competition with the therapeutic IgE

Verhaar, B

The mechanism was suggested to occur at a post-transcriptional or translational step of collagen biosynthesis, though this remains to be confirmed

[PMC free article: PMC3671347] [PubMed: 23761782] 51

Altered regulation of iron metabolism has been shown to play a role in the pathogenesis of HCC, particularly in patients who present with NASH, hemochromatosis, or thalassemia [91, 92]