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screened 1,921 patients with PD for GBA1 mutations and found that carriers of neuropathic Gaucher disease mutations and complex GBA1 alleles exhibited a more rapid decline in Mini-Mental State Examination (MMSE) scores, whereas this association was not observed in carriers of non-neuropathic mutations or risk variants [114]

Attempts to demetallate CuCP with copper-binding ligands In CuCP samples the copper eluted from the Sephadex G25 column in HMW region confirming that metal is strongly bound to the protein

Similarly, pharmacological inhibition of GPX4 by Ras-selective lethal compound 3 (RSL3) blocks the enzymatic detoxification of lipid hydroperoxides, resulting in excessive lipid peroxidation and ferroptotic cell death [56,57,58] (Fig

Most studies and data focus on infertility in women, yet there has been relatively little attention given to the male contribution to infertility which may be a factor for more than half of infertile couples

Circulating tumor cell clustering shapes DNA methylation to enable metastasis seeding

doi: 10.1111/ced.13409