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Extensive research has revealed that animal models with severe mitochondrial OXPHOS deficiencies consistently exhibit significantly shortened lifespans (Barends et al

The multifaceted involvement of tyrosine in these biological processes highlights its potential as a therapeutic target for novel cancer treatment strategies

Alternatively, the multifaceted role of ALA in maintaining cellular redox balance through its interaction with the glutathione (GSH) system should not be overlooked (39)

The balance between fission and fusion proteins regulates these events and changes in their expression levels can result in morphological changes in mitochondria (Hara et al., 2018