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Oxidative Stress and Hair Aging Oxidative stress can damage hair follicles and melanocytes, disrupting the production of melanin and leading to hair graying

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Furthermore, a compound derived from noni induced cell cycle arrest and apoptosis in MCF-7 cells by activating the p21 gene and caspase-7 after 72 h of treatment at a specific concentration

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Unlike other animals lacking autophagy genes, which die in early embryo development (before E7.5) because of issues with proamniotic canal closure, Beclin-1 null mice have a significantly more severe embryonic phenotype (176)