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demonstrated that retrovirus-mediated Zfp488 over-expression could significantly promote an oligodendrogenic fate of differentiating SVZ neuronal stem cells and enhance functional recovery of cuprizone-treated mice (Soundarapandian et al., 2011)

Potential therapies With the deepening understanding of the pathological mechanisms underlying PD, current therapeutic strategies have shifted from purely dopaminergic replacement toward disease-modifying interventions targeting core pathological processes

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Distribution refers to the systemic translocation of drugs from the bloodstream to peripheral tissues

A study by Park et al