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We also describe lncRNAs and miRNAs as epigenetic regulators with potential diagnostic and targeting ability

Many cardiovascular risk factors such as diabetes mellitus, hypertension and hyperlipidemia are demonstrated to stimulate the interaction of Cav-1 and eNOS, reduce nitric oxide production resulting in endothelial dysfunction and subsequently the formation of atherosclerotic lesion 41,42,43

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These trials must be sponsored by the applicant company and supervised by independent third-party organizations