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Traditional surgical, genetic and pharmacological studies have tested systemic actions of circulating androgens, and more recent transgenic approaches have allowed for tests of AR gene function in specific androgen responsive niches contributing to body composition, including: skeletal muscle and surrounding interstitial cells, white and brown adipose, as well as trabecular and cortical bone

doi: 10.2147/PPA.S110632

doi: 10.7196/SAMJ.2016.v106i8.10878 Summary Keywords muscle cramps, insomnia, pruritus, depression, portal hypertension, decompensated cirrhosis Citation Philips CA (2024) Commonly encountered symptoms and their management in patients with cirrhosis