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however, substantial evidence suggests that mitochondrial dysfunction and oxidative stress are key factors in its etiology

Science 292, 15521555

(2008) 23:CD004611

A link also exists between the increase in ROS and the asthma severity

Govallo, immunized cancer patients with extracts of term placental chorionic villi

This transporter facilitates the influx of cystine into the cell, where it is reduced to cysteine, which then participates in the synthesis of glutathione (GSH) through a reaction with GSH [91]