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Description

There are no completed Phase 2 or Phase 3 clinical trials of 5-Amino-1MQ in human participants

Rotating injection sites prevents accumulated irritation

Nature 542 , 352356 (2017)

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The foundational pharmacology paper described 5-Amino-1MQ as a potent, membrane-permeable inhibitor with strong selectivity for NNMT compared with the other methyltransferases tested in that research programme