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et al., 1999

The citrate in excess of mitochondrial requirements is exported in the cytosol, converted into acetyl-CoA by ATP-citrate lyase (ACLY), and used for protein acetylation and lipogenesis

Glutathione, a thiol-reducing agent and antioxidant responsible for the breakdown of H 2 O 2 , is known to be dysregulated in PD patients

Overregulation of fat production can lead to excessive accumulation of fat cells, which in turn leads to obesity (70)

Our L-Carnitine is enriched with green tea to obtain THE ideal combination to optimize fat oxidation during exercise while improving energy and recovery

We have also focused on drug repositioning studies, especially for prevention, because they should be rapidly translated to patients suffering from CIPN