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In vitro models to study confinement-induced responses include micropatterned lines [151], 2D micropatterned substrates [85], uni-axial compression [152], polydimethylsiloxane [153,154,155,156]- or polyacrylamide [90]-based microchannel devices, microniches [157, 158], and natural hydrogels [148, 159]

The stained slides were then observed under an inverted fluorescence microscope (DMi8, Leica, Germany)

Intracellular crystalline particulate material was found in an ultrastructural study in five of 20 investigated FISS, and in one of the five cases was identified as aluminium-based material (Madewell et al., 2001)

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Both Tirzepatide and Semaglutide are at the forefront of peptide therapy for weight loss, but they have a key difference