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40, 41 To avoid cellular and DNA damages, ROS concentration is tightly regulated during liver regeneration, and this process is achieved at least in part by the cytoprotective transcription factor Nrf2

Furthermore, Nrf2 participates in the regulation of metabolism and thus correlates with the production of some important metabolites in the redox system, including GSH and NAPDH (95)

Mease PJ, Gottlieb AB, van der Heijde D, FitzGerald O, Johnsen A, Nys M, Banerjee S, Gladman DD (2017) Efficacy and safety of abatacept, a T-cell modulator, in a randomised, double-blind, placebo-controlled, phase III study in psoriatic arthritis

The incidence and severity of CNS diseases such as AD, PD, and stroke were significantly positively correlated with the degree of piezo1 gene expression