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Moreover, elevated GSH levels can protect tumor cells by reducing the cytotoxic effects of several chemotherapy drugs, including cisplatin, doxorubicin, melphalan, and paclitaxel, ultimately leading to drug resistance [17]

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doi: 10.1038/s41467-023-43728-8 221 SeddonJ

Accordingly, in cancer when MPO-HOCl production is already increased coupled with cyclophosphamide treatment, depletion of GSH via both HOCl and acrolein is likely and may result in substantial oxidative damage inducing both follicular apoptosis and oocyte deterioration (Fig

Injection site reactions (redness, mild swelling) are common with subcutaneous peptide administration and are not specific to GHRP-6

Additionally, histopathologic changes were observed in the testicular tissue