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Walczak MK, Lokhandwala N, Hodge MB, Guay AT

With iron as the catalyst, a large number of LOOHs are produced to destroy the intracellular redox balance and attack biological macromolecules, finally triggering cell death

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These alterations were correlated with motor symptom severity and disease duration, suggesting a potential role of these metabolites as biomarkers of PD progression

Table 1 Targets of glutamine metabolism in the regulation of autoimmune diseases

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