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10.3390/ijms19030907 35 ChanetonB.HillmannP.ZhengL.MartinA

HDAC inhibition by butyrate enhances HIF1s transcriptional activity, leading to the upregulation of genes that support gut barrier integrity, such as those encoding tight junction proteins (e.g., claudins and occludins) (Fachi et al., 2019)

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Materials and Methods Chemicals and Reagents 5-Fluorouracil (Cat# F6627), erastin (Cat# E7781) and ferrostatin-1 (Cat# SML0583) were purchased from Sigma-Aldrich (St

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