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Brain 114 (Pt 5:22832301 Felder CC, Jose PA, Axelrod J (1989) The dopamine-1 agonist, SKF 82526, stimulates phospholipase-C activity independent of adenylate cyclase

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This process leads to an exaggerated function of Ang II due to a decrease in the conversion of Ang II to Ang 1-7, which leads to inflammatory effects and a drastic increase in the production of cytokines, with consequent deleterious effects [19, 24] (Fig

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We propose that the application of modern oncogenomic approaches to cNF may yield valuable insights and allow the identification of putative drug targets to improve the therapeutic prospects of NF1 patients