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A case-control study published in Oral Diseases found that smokers were 5.6 times more likely to develop lip pigmentation than non-smokers, with the risk increasing the longer a person smoked.The result is smokers lips that appear darker, duller, and older than they actually are

Effects of smoking cessation or reduction on hormone profiles and bone turnover in postmenopausal women

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This disruption may contribute to thyroid dysfunction and related symptoms, such as changes in weight, fatigue, and mood disturbances

A Mendelian randomization study