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Suplemento elaborado en territorio de la Unin Europea

Whereas the tumor necrosis factor alpha (TNF-)-mediated activation of MKK4 (SEK1) via its downstream target JNK leads to the induction of apoptotic cell death, the activation of MKK6 activates p38 subgroups of MAPK, which phosphorylate a wide range of potential targets in response to inflammatory cytokines and cellular stress

To count a progeny production, worms were exposed to 75 M acivicin from eggs throughout the experiment

doi: 10.1038/s41467-019-10741-9

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Among the many agents that are used for repletion and depletion of glutathione, NAC and L-buthionine-( S,R )-sulfoximine are, respectively, of particular importance as they exhibit antagonistic effects on a pro-inflammatory signal