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Lancet 389 , 13991409 (2017)

In research studies, changes in antioxidant enzyme activity and cell signaling have been observed

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Freezing and thawing cycles can damage peptide structures and lead to aggregation, reducing efficacy

Rats underwent intravenous administration of 4.5 mg/kg panduratin A, a single oral administration of 45 mg/kg panduratin A, or a multiple oral administration of 45 mg/kg panduratin A-consisted fingerroot extract for 7 consecutive days

These typically resolve with continued use or dose adjustment