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But there is a trade-off: DAC also increases the potential for side effects (more on that below)

Effectiveness of low-fat diet on the levels of insulin-like growth factor-1 and insulin-like growth factor binding proteins: a systematic review and meta-analysis of randomized controlled clinical trials

Perspectives in solubility measurement and interpretation

The short dihexa half life is a pharmacological advantage, not a limitation it allows precise temporal control over receptor activation without accumulation toxicity or prolonged systemic exposure

Further, long-term use of acid-reducing drugs and the anti-diabetes drug metformin and repeated exposure to nitrous oxide have been implicated in vitamin B 12 deficiency (see Drug interactions)