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10.1021/acs.jafc.5b05067 84

5.1.4 Polymorphisms in autophagy and gut microbiota The risk allele ATG16L1 T300A, a single nucleotide polymorphism (SNP) linked to increased CD risk, leads to dysbiosis in mice, causing an increase in Bacteroides and amplifying the Th1 and Th17 immune responses in the gut lamina propria (160)