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These radicals raise peroxidation of lipids which leads to liver disorders such us: 1) Ischemic reperfusion injury (IRI): ROS generated by activated liver cells act as a vital mediator in liver ischemic-reperfusion injury (Zhang W et al., 2007) 2) Alcohol-induced oxidative stress: In ethanol-associated liver disorders, ROS plays an important role (Tan et al., 2020)

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By the term physico-chemically compatible with respect to a component of a parenteral nutrition composition is meant that a disruption of the composition is not observed, as determined by the observation of phase separation, creaming, particulate formation, an increase in the percentage of lipid globules having a diameter greater than 5 m as measured by conventional light scattering, light obscuration, or particle-sizing techniques, or the like