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This muscle-sparing effect distinguishes it from many other fat loss approaches including some GLP-1 medications and severe caloric restriction

By three months some patients begin noticing clearer changes in weight and body composition, especially when combining treatment with exercise and balanced nutrition

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Experimental studies on gastric cancer cell lines CUM-2MD3 and OCUM-12 have found that under hypoxic conditions, GC cells form EMT through autocrine stimulation of TGF factors (172)