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So while it is produced naturally by the body, it can also be supplemented through oral, topical, or intravenous means to enhance its effects

In the CLP-induced SAKI mice model, the treatment of THC can upregulate the expression and activity of SIRT1 and downregulate the expressions of ac-p65 and ac-FoxO1 and improve renal function and renal tissue injury in SAKI mice

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