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Researchers have reported an association between a GSK-3 polymorphism and psychotic symptoms, the regulation of gene expression, lithium responsiveness, and alterations in white-matter microstructure in the context of bipolar illness (57, 58)

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H2O2, a necessary evil for cell signaling

8-OHdG, a key oxidative damage biomarker produced when ROS attack DNA, exhibits significantly elevated levels in uterine fibroid tissue

5-amino-1MQ showed concentration-dependent inhibition of NNMT in fully differentiated adipocytes that could be fit to a 3-parameter sigmoidal dose-response curve with a calculated EC50=2.3+/1.1 M (permeable NNMT inhibitorFIGS

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