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A 2016 study conducted by the University of Southern California and published in the journal Pediatrics came to a sobering conclusion: Older teens who try electronic cigarettes (e-cigarettes) are six times more likely to try combustible cigarettes within two years, compared to those who have never used the devices

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This is because the olfactory bulb, which processes smell information, is directly connected to the amygdala and hippocampus

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Nicotine activates nicotinic acetylcholine receptors, located in brain reward areas, producing the release of neurotransmitters associated with pleasure, such as dopamine

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