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[DOI] [PubMed] [Google Scholar] 3.Miyamoto RG, Elser F, Millett PJ

Damaged liver cells release DAMPs, and gut-derived LPS can activate macrophages by acting on receptors such as TLR4 and RAGE

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These effects are generally dose-dependent and tend to improve as the body adjusts to the medication

CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver