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Description

Introduction Traditionally, vitamin B 12 replacement is administered intramuscularly (IM)

Nature (2016) 536:815

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Two downstream consequences are mechanistically central: nicotinamide is preserved for re-entry into the NAD+ salvage pathway (raising intracellular NAD+ availability), and SAM is preserved for other methylation reactions

The genetic test reveals predispositions related to peptide receptor sensitivity and metabolic response patternsnot a guaranteed prediction of medication outcomes