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Molecules (Basel, Switzerland), 19(11), 1906619077

MOTS-c modulates the FOXO transcription factors and regulates cellular senescence, the state in which aged or damaged cells stop dividing but refuse to die, instead secreting a cocktail of inflammatory signals known as the senescence-associated secretory phenotype (SASP)

Taherian-Fard A, Srihari S, Ragan MA

While these diseases have distinct etiologies and pathologies, they all involve neuronal loss and sustained activation of the brains immune system, including microglia and astrocytes (Ferreira et al., 2013)

Acyl-biotin exchange (ABE) assay The ABE assay was conducted with minor modifications as previously described (Lu et al, 2019)

Severity of OSAS, CPAP and cardiovascular events: A follow-up study