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It was reported that, the expression of DNMT3a was down-regulated when exposure of mouse embryonic fibroblasts to BaP for 2 weeks, while the expression of DNMT1 up-regulated after 4 weeks of exposure, and DNA methylation levels was elevated [152]

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greater mortality was seen in those in whom protein accounted for a lower percentage of total calories.21 Suboptimal cysteine intakes, exacerbating the age-related decline in glutathione levels, could play a mediating role in this phenomenon.4,22 An increase in glycine intake could potentially likewise have a beneficial impact on mortality rates in the elderly, most notably in those with low total protein intake

Mitochondrial distribution was classified into two categories: abnormal mitochondrial distribution in the cytoplasm and normal distribution (Figs

Rheumatology 53 , 104113 (2014)