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2017;169(2):258-272.e17

Oxygen in health and disease: regulation of oxygen homeostasisclinical implications

144 The Warburg effect indicates that lower intratumoral glucose levels can impede tumor growth, which can be achieved through pharmacological intervention and dietary changes such as a KD

Mitochondrial Transmembrane Potential (MTP) assay MTP was assessed using the mitochondrial potential sensitive carbocyanine dye 3,3-dihexyloxacarbocyanine iodide (DiOC6) [46, 47], which accumulates in mitochondria due to their negative membrane potential

Nephrotoxicity of herbal medicine and its prevention

Yet, overproduction of reactive oxygen species (ROS), induced by environmental toxins, inflammation, or mitochondrial dysfunction, overwhelms the cellular antioxidant defense system, resulting in oxidative stress [27]