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Of these, ABCG2 extrudes the major tobacco carcinogen benzo(a)pyrene and its conjugates, and has been identified as the main ABC gene contributing to tobacco smoke-associated cisplatin resistance 35

Additionally, future research should incorporate more granular assessments of national tobacco control policies and socio-cultural contexts to better contextualize behavioral findings and guide country-specific public health interventions

However, modern forms of cannabis may not have these same effects

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