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Figure 2 In February 2023, the patient underwent a PET-CT scan, which revealed further shrinkage of liver masses

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Treatment with the RIPK1 inhibitor Nec-1 concurrently blocks both necroptosis and ferroptosis, and its protective effect is significantly superior to that of ferrostatin-1 or z-VAD alone (145)

Repeated mild lateral fluid percussion brain injury in the rat causes cumulative long-term behavioral impairments, neuroinflammation, and cortical loss in an animal model of repeated concussion

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In addition, Aldh2 / mice showed elevated hippocampal formaldehyde levels produced by mitochondrial sarcosine dehydrogenase and impairment in memory [32], suggesting that ALDH2 deficiency causes an accumulation of endogenous formaldehyde which may result in memory loss in mice