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Davies SM, Bhatia S, Ross JA, Kiffmeyer WR, Gaynon PS, Radloff GA et al

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Most of the studies examining neural function in the euthymic state have noted decreased function in ventrolateral PFC, dorsolateral PFC, and hyperactivation of striatal regions (caudate and putamen) (106)

Given that for GSH the strongest interactions are formed by the C-terminus of the ECG tripeptide, the binding of CG is not unexpected, the preference for GSH, however, confirms that additional binding energy is contributed by residue E, although its side chain can assume multiple conformations (Fig

Similar effects have been observed with the mitochondrial uncoupler BAM15, which enhances mitochondrial oxidative capacity partly by peroxisome proliferator-activated receptor coactivator-1 activation (68)