However, given the fundamental role of energy metabolism in biological processes and current research evidence, investigations focusing on lactate and histone lactylation modifications represent promising research directions for developing therapeutic strategies against metabolic diseases, particularly malignancies
1c) revealed that glycerophosphocholine (VIP: 1.81), N-acetylglycine (VIP: 1.62), creatinine (VIP: 1.33), serine (VIP: 1.33), leucine (VIP:1.31), pyroglutamate (VIP: 1.23), proline (VIP: 1.16), asparagine (VIP:1.04), tyrosine (VIP:1.02) and taurine (1.02) could discriminate the metabolomic profiles of PD patients and HC
albicans by reducing fungal adhesion/invasion and reshaping innate immune cytokine secretion, highlighting its role in vaginal microecological defense against VVC (Niu et al., 2017)
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Resuscitation 179 , 116123 (2022)
NNMT inhibition increases cellular NAD+ levels by 3050%, activating SIRT1-dependent mitochondrial biogenesis and fat oxidation without appetite suppression or thermogenic stimulation
