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It has a certain degree of fidelity in simulating the complex immune environment in body, and is a reliable model that can be applied to tumor vaccine research, which is convenient for clinical development (Zhang Z

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Nerve guidance conduits can restrain trophic molecules released from the distal nerve stump 22 and facilitate ingrowth of Schwann cells 23 and thereby support the regrowth of axons from the proximal nerve stump toward the endoneuroal sheaths within the distal stump, along which the regenerating axons finally reach and reinnervate motor or sensory targets 21

(PubMed) Douaud G, Refsum H, de Jager CA, et al

Two sets of tees for each hole add to the variety (and fun) of the course

Muller et al., 2013)