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2024 May 25:S1534-5807(24)00324-1

Research conducted under Good Laboratory Practice (GLP) standards, clinical trial protocols subject to FDA or EMA oversight, or grant-funded studies requiring regulatory documentation must use reagents and solvents with verifiable quality standards and full traceability

The utilization of non-toxic solvents, biodegradable materials and low-cost green chemicals are central to resources synthesis and processing, considering the green reaction method of these strategies

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Gwinn DM, Shackelford DB, Egan DF, Mihaylova MM, Mery A, Vasquez DS, et al

In both human and mice melanoma cell, it has been seen that ursolic acid activate the expression of the p53 protein and NF-B activation which leads to apoptosis