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This suggests that TCA cycle anaplerosis via pyruvate carboxylase (PC) was stimulated by SAAR

Once there exists an accumulation of DAMPs, it would trigger the amplification of tissue inflammation, leading to more severe inflammation and CD, forming a vicious circle and disrupting the normal physiological function of tissues and organs (Linkermann et al., 2014

This has worried both doctors and patients

When I came home from work, all I could do was eat, watch TV, and fall asleep on the couch

(2) Epigenetic intervention: Targeting epigenetic modifications can reshape the expression profiles of PCD-related genes

In another study, it was shown that HUC occurred among one-third of the study population [13]