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[DOI] [PubMed] [Google Scholar] 113.Durham WJ, Arbogast S, Gerken E, Li YP, Reid MB

These conditions share common mechanisms involving disrupted redox homeostasis, elevated oxidative stress, and impaired detoxification, underscoring the therapeutic potential of strategies aimed at restoring glutathione balance to mitigate disease progression

[PubMed 16770257] 1373

MITF MITF serves as the central hub of the regulatory network of melanin synthesis that is comprised of numerous transcription factors and signaling pathways that modulate the survival, proliferation and differentiation of melanoblasts and melanocytes (37)

10.1016/j.bbrc.2004.05.068

Together, these interconnected pathways establish a compartmentalized antioxidant defense architecture that critically determines ferroptosis sensitivity