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Inter-group comparisons were performed with one-way analysis of variance (ANOVA) and Tukey's post hoc test

The interaction of S1P with S1PR1 improves barrier function, while interaction with S1PR2 causes barrier leakage

The drinks were: 1control: 0.8 g/kg of glucose, 2glutamine: 0.8 g/kg of glucose plus 0.3 g/kg of glutamine, 3a wheat hydrolysate containing 0.8 g/kg of glucose and 26% of glutamine, and 4a whey hydrolysate containing 0.8 g/kg of glucose and 6.6% of glutamine