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However, overexpression of Pfkfb3 activates glycolysis in neurons through the APC/C-Cdh1 pathway, which inhibits the pentose phosphate pathway (PPP), reduces the oxidation of glucose-6-phosphate (G6P), decreases the production of reduced glutathione, and finally leads to oxidative stress and apoptosis (Herrero-Mendez et al., 2009)

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Over time, frequent late-night eating may increase the risk of weight gain and metabolic issues

Joanisse S, McKendry J, Lim C, Nunes EA, Stokes T, McLeod JC, et al

doi: 10.3390/nu15030504 81

Given that our research primarily centers on the incidence of tumors, four tumors with the highest incidence rate were included and analyzed, including breast (morbidity: 11.7% of total cases