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Among the many signaling pathways associated with UC, abnormal activation of the PI3K/Akt signaling pathway may be one of the important mechanisms in the pathogenesis of UC, which has attracted attention for its multiple roles in regulating inflammatory responses, reducing oxidative stress, modulating apoptosis and autophagy, repairing the intestinal mucosal barrier, and maintaining the balance of gut microbiota (Figure 1)

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Within months, Mary noticed a significant improvement in her energy levels and a reduction in chemotherapy-induced side effects

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Future studies should incorporate clinical interviews to conduct comparisons with healthy students

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