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In vitro testing in an HBV cell-based model confirmed retention of IDR activity against tested variants, suggesting that these SNPs have no apparent influence on HBsAg declines in subjects treated with IDR

Chronic treatment of rats results in liver tumors (Schulte-Hermann and Parzefall 1980

Iron and Redox Cycling

Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases

Gundersen TD, Jrgensen N, Andersson AM, et al

Recent controlled RCTs have reported a (modest) reduction in hepatic steatosis on imaging with canagliflozin (169) and dapagliflozin (170) in patients with T2DM and NAFLD