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Alzheimer disease: curly fibers and tangles in organs other than brain

It remains to be established if free radicals are involved in the pathogenesis of glutathione synthetase deficiency and if patients with low levels of glutathione are more sensitive to oxidative stress

Under non-reducing conditions, Cys49 and Cys53 form a disulfide bond that prevents the R2R3 MYB domain from binding DNA (Williams and Grotewold, 1997

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