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10.1038/nrc3860 178 TsaiH

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N-Acetyl-l-cysteine enhances ex-vivo amplification of deciduous teeth dental pulp stem cells

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Chemoreceptors located on the vagus nerve can sense and react to compounds of microbial origin [59], with SCFAs such as butyrate shown to directly activate the afferent fibres on the VN [60]

Ammonia produces its deleterious effects through direct and indirect effects on cells, including but not limited to pH changes, altered metabolism, potassium homeostasis disruption, mitochondrial dysfunction, oxidative stress, inflammation, compromised oxygen homeostasis and dysregulation of neurotransmission