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Regul Toxicol Pharmacol 96:127134 Iskandar AR, Titz B, Sewer A, Leroy P, Schneider T, Zanetti F, Mathis C, Elamin A, Frentzel S, Schlage W, Martin F, Peitsch MC, Hoeng J (2017) Systems toxicology meta-analysis of in vitro assessment studies: biological impact of a modified-risk tobacco product aerosol compared with cigarette smoke on human organotypic cultures of the respiratory tract

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"While e-cigarette vapor does not contain many of the toxic substances that are known to be present in cigarette smoke, it's still important for us to figure out and to minimize the potential dangers that are associated with e-cigarettes." Previous studies have found low levels of aldehydes, chemical compounds that can cause oxidative stress and cell damage, in e-cigarette "smoke." But until now, no one has looked for free radicals, the main source of oxidative stress from cigarette smoke

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