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Cancer risk associated with use of metformin and sulfonylurea in type 2 diabetes: a meta-analysis

Menzie, J., Pan, C., Prentice, H

The metabolic changes belonging to the Warburg effect can be influenced by the known physiological hormetic triggers that could serve as primary and perhaps secondary preventive interventions (Jazvinak Jembrek et al., 2021)

For example, the C-terminal tyrosine residue is particularly critical because it significantly promotes tyrosine binding and inhibition by changing the conformation of the enzyme (Kose and Oncel, 2022)

This review will provide inspiration for the structural modification of IKK inhibitors based on the skeleton of natural products or chemical synthesis and further phytochemistry investigations

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