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It is apparent from these studies that in ALS there is communication between motor neurons, astrocytes, and distinct immune cells with consequent activation at sites of neuronal injury

Russell and Brunekreef 2009)

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Mitochondrial dysfunction and cell growth disorder by GSTP silencing, and their restoration by ROS elimination In addition to increasing the ROS level, comparative proteomics also suggested mitochondrial dysfunction due to GSTP-silencing

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