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Nat Cell Biol 13(3):184190 Tan YB, Lello LS, Liu X, Law Y-S, Kang C, Lescar J et al (2022) Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold

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Side-effects range from mild (nausea, injection-site discomfort) to serious and even life-threatening (allergic reactions, liver injury, systemic inflammatory response, endotoxin-related events)